GPI / Unconjugated /
GPI / Unconjugated /
Product Details
Supplier | Bethyl Laboratories | |
---|---|---|
Catalog #: | A303-753A-T-20UL (View supplier product page) | |
Size | 20 μl | |
Price | $124.00 | |
Antigen | GPI | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | IHC, IP, WB | |
Description | Rabbit anti-GPI Antibody, Affinity Purified |
About GPI and Purified
GPI | This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] |
---|
Citations
Reviews & Ratings
Purified Excitation and Emission Spectra
$124.00
Supplier Page
Supplier Page