CCR7 / Oligo / 4B12

Product Details
Supplier BioLegend
Catalog #: 120131 (View supplier product page)
Size 10UG
Price $369.00
Antigen CCR7
Clone 4B12
Host Rat
Isotype IgG2a κ
Conjugate Oligo
Target Species Mouse
Applications Proteogenomics
Description TotalSeq-C0377 anti-mouse CD197 (CCR7)
About CCR7 and Oligo
CCR7 The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
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Oligo Excitation and Emission Spectra