CD124 / Oligo / I015F8

Citations: (1)
Product Details
Supplier BioLegend
Catalog #: 144809 (View supplier product page)
Size 10 μg
Price $369.00
Antigen CD124
Clone I015F8
Host Rat
Isotype IgG2b κ
Conjugate Oligo
Target Species Mouse
Applications Proteogenomics
Description TotalSeq-A0916 anti-mouse CD124 (IL-4Ralpha)
About CD124 and Oligo
CD124 This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
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Oligo Excitation and Emission Spectra