CD209 Monoclonal / Alexa Fluor 647 / UW60.1

Product Details
Supplier EXBIO
Catalog #: A6-640-T100 (View supplier product page)
Size 100 Tests
Price $220.00
Antigen CD209
Clone UW60.1
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 647
Target Species Human
Applications FC, IHC, ICC
Description CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).
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Alexa Fluor 647 Excitation and Emission Spectra