CD274 Monoclonal / APC / 29E.2A3

Product Details
Supplier EXBIO
Catalog #: 1A-177-T100 (View supplier product page)
Size 100 Tests
Price $220.00
Antigen CD274
Clone 29E.2A3
Host Mouse
Isotype IgG2b
Conjugate APC
Target Species Human, Non-Human Primate
Applications FC, IHC-Fr
Description CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its ligand CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor(s) for CD274 is likely.
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APC Excitation and Emission Spectra