Integrin alpha 4 beta 7 Monoclonal / Unconjugated / DATK32

Product Details
Supplier EXBIO
Catalog #: 11-747-C100 (View supplier product page)
Size 100 μg
Price $80.00
Antigen Integrin alpha 4 beta 7
Clone DATK32
Host Rat
Isotype IgG2a κ
Conjugate Unconjugated
Target Species Mouse
Applications Functional, FC, IP, IHC-Fr
Description Integrin alpha 4 / beta 7 (CD49d / Ly69) , also known as LPAM-1 (Lymphocyte Peyer´s patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer´s patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.
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Purified Excitation and Emission Spectra