Glutamate Dehydrogenase / Unconjugated /
Glutamate Dehydrogenase / Unconjugated /
Product Details
Supplier | Elabscience | |
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Catalog #: | E-AB-62764-60UL (View supplier product page) | |
Size | 60 μl | |
Price | $156.00 | |
Antigen | Glutamate Dehydrogenase | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human, Mouse, Rat | |
Applications | WB, IHC | |
Description | GLUD1 Polyclonal Antibody |
About Glutamate Dehydrogenase and Purified
Glutamate Dehydrogenase | This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016] |
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Citations
Reviews & Ratings
Purified Excitation and Emission Spectra
$156.00
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