GFR alpha-1 / Unconjugated /

Product Details
Supplier Elabscience
Catalog #: E-AB-15685-20UL (View supplier product page)
Size 20 μl
Price $84.00
Antigen GFR alpha-1
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, ELISA
Description GFRA1 Polyclonal Antibody
About GFR alpha-1 and Purified
GFR alpha-1 This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
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Purified Excitation and Emission Spectra