c-Met / Alexa Fluor 680 /
c-Met / Alexa Fluor 680 /
Product Details
| Supplier | Bioss | |
|---|---|---|
| Catalog #: | bs-0668R-A680 (View supplier product page) | |
| Size | 100 μl | |
| Price | $468.00 | |
| Antigen | c-Met | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Alexa Fluor 680 | |
| Target Species | Human, Mouse, Rat | |
| Applications | FC | |
| Description | Met (c Met) Polyclonal Antibody, ALEXA FLUOR 680 Conjugated |
About c-Met and Alexa Fluor 680
| c-Met | This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016] | |
|---|---|---|
| Alexa Fluor 680 | Alexa Fluor™ 680 (AF680, Alexa 680) has an excitation peak at 679 nm and an emission peak at 702 nm, and is spectrally similar to Cy®5.5 (GE Healthcare), IR680® (Licor), iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 680 is commonly used for flow cytometry, fluorescence microscopy and super-resolution microscopy. |
Citations
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