MLKL / Biotin /

Product Details
Supplier Epigentek
Catalog #: A51164-100UG (View supplier product page)
Size 100 μg
Price $433.00
Antigen MLKL
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human
Applications ELISA
Description MLKL Polyclonal Antibody, Biotin Conjugated. This antibody is a Rabbit IgG that reacts with Human. Uniprot ID is Q8NB16.
About MLKL and Biotin
MLKL This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015]
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Biotin Excitation and Emission Spectra