HLA DRB4 / HRP /

Product Details
Supplier Epigentek
Catalog #: A59385-100UG (View supplier product page)
Size 100 μg
Price $433.00
Antigen HLA DRB4
Clone
Host Rabbit
Isotype IgG
Conjugate HRP
Target Species Human
Applications ELISA
Description HLA-DRB4 Polyclonal Antibody, HRP Conjugated. This antibody is a Rabbit IgG that reacts with Human. Uniprot ID is P13762.
About HLA DRB4 and HRP
HLA DRB4 HLA-DRB4 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. There are multiple pseudogenes of this gene. [provided by RefSeq, Feb 2020]
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HRP Excitation and Emission Spectra