CD11b / V500 / M1/70

Citations: (7)
Product Details
Supplier BD Biosciences
Catalog #: 562128 (View supplier product page)
Size 25 μg
Price $190.00
Antigen CD11b
Clone M1/70
Host Rat
Isotype IgG2b κ
Conjugate V500
Target Species Human, Mouse
Applications FC
Description CD11b Horizon V500 M1/70 25ug
About CD11b and V500
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
V500 V500 (Horizon V500) from BD Biosciences has an excitation peak at 415 nm and an emission peak at 500 nm. It is spectrally similar to AmCyan.
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V500 Excitation and Emission Spectra