Glutamate Dehydrogenase / Unconjugated /

Product Details
Supplier Elabscience
Catalog #: E-AB-19915-200UL (View supplier product page)
Size 200 μl
Price $481.00
Antigen Glutamate Dehydrogenase
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, ELISA
Description GLUD1 Polyclonal Antibody
About Glutamate Dehydrogenase and Purified
Glutamate Dehydrogenase This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]
Citations
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra