CD11b / Alexa Fluor 700 / ICRF44 (also known as 44)

Citations: (8)
Product Details
Supplier BD Biosciences
Catalog #: 557918 (View supplier product page)
Size 100 μg
Price $362.00
Antigen CD11b
Clone ICRF44 (also known as 44)
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 700
Target Species Baboon, Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description Hu CD11B Alexa 700 ICRF44 100ug
About CD11b and Alexa Fluor 700
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra