CD45 / Unconjugated / 2D1

Citations: (13)
Product Details
Supplier BD Biosciences
Catalog #: 347460 (View supplier product page)
Size 100 Tests
Price $325.00
Antigen CD45
Clone 2D1
Host Mouse
Isotype IgG1 κ
Conjugate Unconjugated
Target Species Human
Applications FC
Description CD45 Purified 2D1 100 Tests RUO/GMP
About CD45 and Purified
CD45 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
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Purified Excitation and Emission Spectra