CD11b / PE / ICRF44 (also known as 44)

Citations: (7)
Product Details
Supplier BD Biosciences
Catalog #: 561001 (View supplier product page)
Size 25 Tests
Price $112.00
Antigen CD11b
Clone ICRF44 (also known as 44)
Host Mouse
Isotype IgG1 κ
Conjugate PE
Target Species Baboon, Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description Hu CD11B PE ICRF44 25Tst
About CD11b and PE
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra