CD8a / PE-CF594 / RPA-T8

Citations: (3)
Product Details
Supplier BD Biosciences
Catalog #: 562311 (View supplier product page)
Size 25 Tests
Price $190.00
Antigen CD8a
Clone RPA-T8
Host Mouse
Isotype IgG1 κ
Conjugate PE-CF594
Target Species Baboon, Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description Hu CD8 PE-CF594 RPA-T8 25Tst
About CD8a and PE-CF594
CD8a The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
PE-CF594 PE-CF®594 from BD Biosciences has an excitation peak at 496 nm and an emission peak at 612 nm. It is an alternative to PE-Dazzle 594, PE-Alexa 610, PE-eFluor™ 610 and PE-CF®594.
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PE-CF594 Excitation and Emission Spectra