MART-1 / Alexa Fluor 700 / M2-7C10

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-33148AF700 (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen MART-1
Clone M2-7C10
Host Mouse
Isotype IgG2b κ
Conjugate Alexa Fluor 700
Target Species Human, Mouse (Negative), Rat (Negative)
Applications WB, FC, ICC/IF, ELISA, IHC-Fr, IHC-P, IP, IHC
Description This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
About MART-1 and Alexa Fluor 700
MART-1 Located in endoplasmic reticulum membrane; melanosome; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra