Protocadherin gamma B2 / ATTO 390 / S148-30

Product Details
Supplier Rockland Immunochemicals
Catalog #: 200-367-W66-100UG (View supplier product page)
Size 100 μg
Price $445.00
Antigen Protocadherin gamma B2
Clone S148-30
Host Mouse
Isotype IgG1
Conjugate ATTO 390
Target Species Mouse
Applications ELISA, WB
Description Protocadherin Gamma B2 Antibody ATTO 390
About Protocadherin gamma B2 and ATTO 390
Protocadherin gamma B2 This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
ATTO 390 ATTO 390 from ATTO-TEC has an excitation peak at 390 nm and an emission peak at 448 nm. It is a novel fluorescent label with a coumarin structure. Characteristic features of the label are high fluorescence quantum yield, large Stokes-shift, good photo-stability, and low molecular weight.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

ATTO 390 Excitation and Emission Spectra