GM-CSF Monoclonal / PE-Dazzle 594 / MP1-22E9

Product Details
Supplier Sony
Catalog #: 3127110 (View supplier product page)
Size 100 μg
Price $394.00
Antigen GM-CSF
Clone MP1-22E9
Host Rat
Isotype IgG2a κ
Conjugate PE-Dazzle 594
Target Species Mouse
Applications FC
Description PE/Dazzle 594 anti-mouse GM-CSF
About GM-CSF and PE-Dazzle 594
GM-CSF The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq, Aug 2020]
PE-Dazzle 594 PE-Dazzle® 594 (RPE-Dazzle 594) from Biolegend is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Dazzle 594. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Dazzle 594, which emitts light that can be captured with a 610/20 nm bandpass filter. PE-Dazzle 594 has an excitation peak at 565 nm and an emission peak at 610 nm, and is suitable alternative to PE-Texas Red, PE-eF610, PE-Alexa Fluor™ 610 or PE-CF®594.
Citations
Additional
Sources
Reviews & Ratings
PE-Dazzle 594 Excitation and Emission Spectra