CD62L / Alexa Fluor 405 / DREG-56

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-42795AF405 (View supplier product page)
Size 0.1 ml
Price $429.00
Antigen CD62L
Clone DREG-56
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 405
Target Species Human
Applications WB, FC, IHC-Fr, IHC
Description The mouse monoclonal antibody DREG56 recognizes CD62L/ L-selectin, a 65-76 kDa cell surface protein, expressed by neutrophils, monocytes, and subsets of T, B, and NK cells, that interacts with specific carbohydrates exposed on activated endothelial cells. HLDA V; WS Code S056
About CD62L and Alexa Fluor 405
CD62L This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra