CD355 / PE-Vio615 / REA1225

Citations: (1)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-124-092 (View supplier product page)
Size 100 tests in 200 µL
Price $335.00
Antigen CD355
Clone REA1225
Host Human
Isotype IgG1
Conjugate PE-Vio615
Target Species Human
Applications FC
Description Clone REA1225 recognizes the human CD355 protein, a class I–restricted T cell–associated molecule (CRTAM). It is expressed on activated class I MHC restricted T cells, including CD8+ T cells and NKT cells and binds nectin-like protein 2 (NecI2). The binding of CRTAM and NecI2 triggers cytotoxity of NK cells and IFN-γ secretion by CD8+ T cells. | Additional information: Clone REA1225 displays negligible binding to Fc receptors.
About CD355 and PE-Vio615
CD355 The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009]
PE-Vio615 PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594
Citations
PMID 15811952
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PE-Vio615 Excitation and Emission Spectra