FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-123-671 (View supplier product page)
	Size	100 tests in 200 µL
	Price	$265.00
	Antigen	Mannose Receptor
	Clone	DCN228
	Host	Mouse
	Isotype	IgG1,κappa
	Conjugate	FITC
	Target Species	Human
	Applications	MICS (MACSima Imaging Cyclic Staining), FC, IF, IHC
	Description	The mannose receptor (MR), also known as macrophage MR or CD206, is a 162–175 kDa type I membrane protein. It contains an N-terminal cystein-rich domain and eight C-type lectin-like domains (CTLDs), beside a transmembrane and a cytoplasmic domain. CD206 is expressed by macrophages, dendritic cells, and subsets of endothelial cells, but not on monocytes. The MR recognizes multiple mainly microbial carbohydrates with mannose, fucose, or N-acetyl glucosamine residues. The MR mediates endocytosis and phagocytosis, linked to antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity.

$265.00
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Mannose Receptor / FITC / DCN228