CD185 / APC / REA103
CD185 / APC / REA103
Citations:
(7)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-122-926 (View supplier product page) | |
Size | 100 tests in 200 µL | |
Price | $325.00 | |
Antigen | CD185 | |
Clone | REA103 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | APC | |
Target Species | Human | |
Applications | FC, Mass Cytometry | |
Description | Clone REA103 recognizes human CD185, which is a 42 kDa G-protein–coupled chemokine receptor and is also known as CXCR5, monocyte-derived receptor 15 (MDR15), or Burkitt lymphoma receptor-1 (BLR1). BLR-1 was originally identified on cells of Burkitt´s lymphoma and B cells. B cell attracting chemokine 1 (BCA-1), also known as B-lymphocyte chemoattractant (BLC) or CXCL13, is the ligand of CD185. It is further expressed on central memory CD4 T cells, T folicular helper cells, and on a migratory population of skin-derived dendritic cells. | Additional information: Clone REA103 displays negligible binding to Fc receptors. |
About CD185 and APC
CD185 | This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] | |
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APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
PMID 18056361 | ||
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PMID 21471443 | ||
PMID 7913842 | ||
PMID 11069061 | ||
PMID 8978608 | ||
PMID 27323685 | ||
PMID 29196729 | ||
Additional Sources |
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Reviews & Ratings
APC Excitation and Emission Spectra
$325.00
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