FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-123-303 (View supplier product page)
	Size	30 tests in 60 µL
	Price	$95.00
	Antigen	HLA-A2
	Clone	REA517
	Host	Human
	Isotype	IgG1
	Conjugate	Biotin
	Target Species	Human
	Applications	FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
	Description	Clone REA517 recognizes the class I human leukocyte antigen A2 (HLA-A2). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and a soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of three domains, one of which comprises the peptide binding groove. Antigens binding to class I molecules are 8–10 amino acids long and play an important role in recognition of virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells. \| Additional information: Clone REA517 displays negligible binding to Fc receptors.

$95.00
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HLA-A2 / Biotin / REA517