ATP7b Monoclonal / DyLight 488 / S62-29

Product Details
Supplier Stressmarq
Catalog #: SMC-399D-DY488 (View supplier product page)
Size 100 μg
Price $334.00
Antigen ATP7b
Clone S62-29
Host Mouse
Isotype IgG1
Conjugate DyLight 488
Target Species Human, Mouse, Rat
Applications WB, IHC, IP, ICC/IF
Description Mouse Anti-Human Copper Transporting ATPase 2 Monoclonal IgG1
About ATP7b and DyLight 488
ATP7b This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. [provided by RefSeq, Dec 2019]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra