Cav1.2 Monoclonal / DyLight 488 / S57-46

Product Details
Supplier Stressmarq
Catalog #: SMC-300D-DY488 (View supplier product page)
Size 100 μg
Price $334.00
Antigen Cav1.2
Clone S57-46
Host Mouse
Isotype IgG1
Conjugate DyLight 488
Target Species Hamster, Human, Mouse, Rat
Applications WB, IHC, IP, ICC/IF, Microarray
Description Mouse Anti-Rabbit Cav1.2 Monoclonal IgG1
About Cav1.2 and DyLight 488
Cav1.2 This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra