ErbB4 Polyclonal / DyLight 488 /

Product Details
Supplier Stressmarq
Catalog #: SPC-1139D-DY488 (View supplier product page)
Size 100 μl
Price $375.00
Antigen ErbB4
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 488
Target Species Human, Mouse
Applications WB, Microarray
Description Rabbit Anti-Human ErbB4 Polyclonal
About ErbB4 and DyLight 488
ErbB4 This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra