LGR5 / Brilliant Ultraviolet 496 / 8F2

Product Details
Supplier BD Biosciences
Catalog #: 750279 (View supplier product page)
Size 50 μg
Price $538.00
Antigen LGR5
Clone 8F2
Host Rat
Isotype IgG2b κ
Conjugate Brilliant Ultraviolet 496
Target Species Human
Applications FC
Description Hu Lgr5 BUV496 8F2 50ug
About LGR5 and Brilliant Ultraviolet 496
LGR5 The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Brilliant Ultraviolet 496 Brilliant™ UltraViolet 496 (BUV496) is a blue-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 515/30 bandpass filter. BUV496 has an excitation peak at 348 nm and an emission peak at 496 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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Brilliant Ultraviolet 496 Excitation and Emission Spectra