CD276 / Brilliant Ultraviolet 496 / 7-517

Product Details
Supplier BD Biosciences
Catalog #: 749897 (View supplier product page)
Size 50 μg
Price $538.00
Antigen CD276
Clone 7-517
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Ultraviolet 496
Target Species Human
Applications FC
Description Hu CD276 BUV496 7-517 50ug
About CD276 and Brilliant Ultraviolet 496
CD276 The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Brilliant Ultraviolet 496 Brilliant™ UltraViolet 496 (BUV496) is a blue-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 515/30 bandpass filter. BUV496 has an excitation peak at 348 nm and an emission peak at 496 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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Brilliant Ultraviolet 496 Excitation and Emission Spectra