CD43 / Brilliant Ultraviolet 805 / L60

Product Details
Supplier BD Biosciences
Catalog #: 749227 (View supplier product page)
Size 50 μg
Price $538.00
Antigen CD43
Clone L60
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Ultraviolet 805
Target Species Human
Applications FC
Description Hu CD43 BUV805 L60 50ug
About CD43 and Brilliant Ultraviolet 805
CD43 This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
Brilliant Ultraviolet 805 Brilliant™ UltraViolet 805 (BUV805) is a infrared-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 820/60 bandpass filter. BUV805 has an excitation peak at 498 nm and an emission peak at 797 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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Brilliant Ultraviolet 805 Excitation and Emission Spectra