CD35 / Brilliant Ultraviolet 805 / E11

Product Details
Supplier BD Biosciences
Catalog #: 749148 (View supplier product page)
Size 50 μg
Price $538.00
Antigen CD35
Clone E11
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Ultraviolet 805
Target Species Human
Applications FC
Description Hu CD35 BUV805 E11 50ug
About CD35 and Brilliant Ultraviolet 805
CD35 This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020]
Brilliant Ultraviolet 805 Brilliant™ UltraViolet 805 (BUV805) is a infrared-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 820/60 bandpass filter. BUV805 has an excitation peak at 498 nm and an emission peak at 797 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Brilliant Ultraviolet 805 Excitation and Emission Spectra