CD91 / Brilliant Ultraviolet 737 / A2MR-α2

Product Details
Supplier BD Biosciences
Catalog #: 748695 (View supplier product page)
Size 50 μg
Price $538.00
Antigen CD91
Clone A2MR-α2
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Ultraviolet 737
Target Species Human
Applications FC
Description Hu CD91 BUV737 A2MR-A2 50ug
About CD91 and Brilliant Ultraviolet 737
CD91 This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]
Brilliant Ultraviolet 737 Brilliant™ UltraViolet 737 (BUV737) is a near infrared-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 740/35 bandpass filter. BUV737 has an excitation peak at 498 nm and an emission peak at 732 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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Brilliant Ultraviolet 737 Excitation and Emission Spectra