CD62L / Brilliant Violet 750 / SK11 (also known as Anti-Leu-8)

Product Details
Supplier BD Biosciences
Catalog #: 747199 (View supplier product page)
Size 50 μg
Price $538.00
Antigen CD62L
Clone SK11 (also known as Anti-Leu-8)
Host Mouse
Isotype IgG2a κ
Conjugate Brilliant Violet 750
Target Species Human
Applications FC
Description Hu CD62L BV750 SK11 50ug
About CD62L and Brilliant Violet 750
CD62L This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Brilliant Violet 750 Brilliant™ Violet 750 (BV750) is a red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 780/60 bandpass filter with a 740 LP dichroic mirror. BV750 has an excitation peak at 405 nm and an emission peak at 750 nm. Due to its unique Stokes shift, no dyes have identical or near identical excitation and emission spectrums. BV750 exhibits a medium level of brightness and is most often used in flow cytometry. Older instruments may not be set up for a dye with such a large Stokes shift, however BV750 is especially well suited for spectral cytometers or sorters. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Brilliant Violet 750 Excitation and Emission Spectra