CD45 / Brilliant Ultraviolet 805 / D058-1283

Citations: (4)
Product Details
Supplier BD Biosciences
Catalog #: 742055 (View supplier product page)
Size 50 μg
Price $538.00
Antigen CD45
Clone D058-1283
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Ultraviolet 805
Target Species Baboon, Cynomolgus macaque, Rhesus macaque
Applications FC
Description NHP CD45 BUV805 D058-1283 50ug
About CD45 and Brilliant Ultraviolet 805
CD45 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Brilliant Ultraviolet 805 Brilliant™ UltraViolet 805 (BUV805) is a infrared-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 820/60 bandpass filter. BUV805 has an excitation peak at 498 nm and an emission peak at 797 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Brilliant Ultraviolet 805 Excitation and Emission Spectra