CD86 / Brilliant Ultraviolet 563 / PO3
CD86 / Brilliant Ultraviolet 563 / PO3
Product Details
Supplier | BD Biosciences | |
---|---|---|
Catalog #: | 741285 (View supplier product page) | |
Size | 50 μg | |
Price | ||
Antigen | CD86 | |
Clone | PO3 | |
Host | Rat | |
Isotype | IgG2b κ | |
Conjugate | Brilliant Ultraviolet 563 | |
Target Species | Mouse | |
Applications | FC | |
Description | Ms CD86 BUV563 PO3 50ug |
About CD86 and Brilliant Ultraviolet 563
CD86 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] | |
---|---|---|
Brilliant Ultraviolet 563 | Brilliant™ UltraViolet 563 (BUV563) is a green-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 585/15 bandpass filter. BUV563 has an excitation peak at 348 nm and an emission peak at 563 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings. |