CD14 / Brilliant Ultraviolet 737 / M5E2

Citations: (2)
Product Details
Supplier BD Biosciences
Catalog #: 612764 (View supplier product page)
Size 25 Tests
Price $240.00
Antigen CD14
Clone M5E2
Host Mouse
Isotype IgG2a κ
Conjugate Brilliant Ultraviolet 737
Target Species Baboon, Canine, Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description Hu CD14 BUV737 M5E2 25Tst
About CD14 and Brilliant Ultraviolet 737
CD14 The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
Brilliant Ultraviolet 737 Brilliant™ UltraViolet 737 (BUV737) is a near infrared-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 740/35 bandpass filter. BUV737 has an excitation peak at 498 nm and an emission peak at 732 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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Brilliant Ultraviolet 737 Excitation and Emission Spectra