CD8a / Alexa Fluor 405 / 76-2-11

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-28237AF405 (View supplier product page)
Size 0.25 ml
Price $619.00
Antigen CD8a
Clone 76-2-11
Host Mouse
Isotype IgG2a κ
Conjugate Alexa Fluor 405
Target Species Porcine
Applications IHC-P, IHC-Fr, FC, IHC
Description Porcine CD8a, Mr 32-34 kDa
About CD8a and Alexa Fluor 405
CD8a The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra