HAP1 / Alexa Fluor 405 / 1B6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB110-74569AF405 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen HAP1
Clone 1B6
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 405
Target Species Human, Mouse, Rat
Applications WB, FC, ICC/IF, IHC-Fr, IHC-P, IHC
Description This is specific for isoforms A and B.
About HAP1 and Alexa Fluor 405
HAP1 Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra