CaMKII alpha/beta / Alexa Fluor 405 / 22B1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB110-96869AF405 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CaMKII alpha/beta
Clone 22B1
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 405
Target Species Human, Mouse, Rat
Applications ICC/IF, WB, ELISA, IHC-P, IHC
Description This antibody is specific for a and B subunits of CaMKII only when they are phosphorylated at Thr-286/287 (in B).
About CaMKII alpha/beta and Alexa Fluor 405
CaMKII alpha/beta The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra