SHP2 / Alexa Fluor 594 / OTI3F2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-74173AF594 (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen SHP2
Clone OTI3F2
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 594
Target Species Canine, Human
Applications WB, FC
Description Mouse SHP-2/PTPN11 antibody [Alexa Fluor 594] detects Human, Canine
About SHP2 and Alexa Fluor 594
SHP2 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
Alexa Fluor 594 Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive.
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Alexa Fluor 594 Excitation and Emission Spectra