PD-1 / Alexa Fluor 594 / PDCD1/1410R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54570AF594 (View supplier product page)
Size 0.1 ml
Price $529.00
Antigen PD-1
Clone PDCD1/1410R
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 594
Target Species Human
Applications FC, IHC, ICC/IF, IHC-P
Description Rabbit PD-1 antibody [Alexa Fluor 594] detects Human
About PD-1 and Alexa Fluor 594
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
Alexa Fluor 594 Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive.
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Alexa Fluor 594 Excitation and Emission Spectra