Nse2 / Alexa Fluor 594 / OTI6A6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-73070AF594 (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen Nse2
Clone OTI6A6
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 594
Target Species Human
Applications WB, FC, ICC/IF
Description Mouse Nse2 antibody [Alexa Fluor 594] detects Human
About Nse2 and Alexa Fluor 594
Nse2 This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017]
Alexa Fluor 594 Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive.
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Alexa Fluor 594 Excitation and Emission Spectra