CD321 / Alexa Fluor 350 / RM0116-1M21

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-22494AF350 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CD321
Clone RM0116-1M21
Host Rat
Isotype IgG2b
Conjugate Alexa Fluor 350
Target Species Mouse
Applications WB
Description This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant protein of extracellular domain of JAM-A.
About CD321 and Alexa Fluor 350
CD321 Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra