CD49b / Alexa Fluor 350 / 16B4

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50144AF350 (View supplier product page)
Size 0.1 ml
Price $449.00
Antigen CD49b
Clone 16B4
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 350
Target Species Human
Applications FC, ELISA, IHC, ICC/IF
Description 16B4 can be used to IP a non-reducible alpha subunit from I(125) surface labelled Human cell line extract. It is specific to the alpha 2 subunit by relative expression of antigen on various cell lines by FACS, and its recognition of affinity purified alpha 2 beta 1 in DB.
About CD49b and Alexa Fluor 350
CD49b This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra