IL-12 R beta 1 / Alexa Fluor 350 / OTI1A6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-71033AF350 (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen IL-12 R beta 1
Clone OTI1A6
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 350
Target Species Human
Applications WB
Description Mouse IL-12 R beta 1 antibody reacts with Human [Alexa Fluor 350]
About IL-12 R beta 1 and Alexa Fluor 350
IL-12 R beta 1 The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra