HLA-DOB / DyLight 594 / DOB 10E6/5

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50420DL594 (View supplier product page)
Size 0.1 ml
Price $449.00
Antigen HLA-DOB
Clone DOB 10E6/5
Host Mouse
Isotype IgG1
Conjugate DyLight 594
Target Species Human
Applications WB, ELISA
Description Mouse HLA DOB antibody [DyLight 594] reacts with Human
About HLA-DOB and DyLight 594
HLA-DOB HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
DyLight 594 DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 594 Excitation and Emission Spectra