Granzyme B / Alexa Fluor 594 / B18.1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-97525AF594 (View supplier product page)
Size 0.1 ml
Price $509.00
Antigen Granzyme B
Clone B18.1
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 594
Target Species Human
Applications WB, FC, IHC, ICC/IF, IHC-P, IHC-Fr
About Granzyme B and Alexa Fluor 594
Granzyme B This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]
Alexa Fluor 594 Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive.
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Alexa Fluor 594 Excitation and Emission Spectra