CD44 / Alexa Fluor 405 / OX-50

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB600-1317AF405 (View supplier product page)
Size 0.1 ml
Price $509.00
Antigen CD44
Clone OX-50
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 405
Target Species Rat
Applications IHC-P, FC, IHC-Fr, IHC
Description This recognizes the rat CD44 cell surface antigen, expressed by T cells, B cells, macrophages and thymocytes.
About CD44 and Alexa Fluor 405
CD44 The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra