CD16 / DyLight 594 / DJ130c

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-64346DL594 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen CD16
Clone DJ130c
Host Mouse
Isotype IgG1
Conjugate DyLight 594
Target Species Human
Applications FC, IHC, IHC-P, IHC-Fr
Description NB100-64346 recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. DJ130c recognizes all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the DJ130c antibody recognizes an epitope in the first membrane-distal domain of CD16 and recognizes both CD16A and CD16B.
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DyLight 594 Excitation and Emission Spectra